Blood samples of 103 SLE patients and 100 healthy individuals were collected. The present study aimed to determine whether single nucleotide polymorphism (SNP) in the promoter region of IL-6 gene (-174G/ C) plays an important role in the SLE in Iraqi population.
Systemic lupus erythematosus (SLE) is a systemic autoimmune disorder that affects many organs and is characterized by cytokine imbalance and hereditary factors that give a predisposition to the diseases development. Microbial study of Trichophyton rubrum isolated from various Tinea infections. Keywords: Trichiphyton rubrum, Tinea Infections, dermatophytesĬitation: Shabaa RAH. In Conclusion Tinea corporis is the most dermatophytosis caused by Trichiphyton rubrum and Nystatin is the most effective antifungal drug towered it. All of the Trichiphyton rubrum isolates were sensitive to Nystatin (NS 100 IU), Amphotericin-B (AP 100 IU) and Itraconazole (IT 10µg), and resistant to Clotrimazole (CC 10µg), Ketoconazole (KT 10µg), and Fluconazole (FLC 10µg). Tinea corporis was the most common clinical type of Trichiphyton rubrum infection with incidence of 9 (36%). The results showed that from all the clinical specimens (73), included in this study 25 (34.2%) were positive for Trichiphyton rubrum. The positive specimens for Trichiphyton rubrum were tested for susceptibility towards different antifungal drugs. All the clinical specimens were cultured onto sabouraud dextrose agar plates and potato dextrose agar plates and identified using cultural and microscopic features. Seventy-three Tinea infections specimens were included in this study. This study was aimed to isolate and identify Trichiphyton rubrum from different Tinea infection using morphological features including scanning electron microscope examination and to evaluate its sensitivity towards several antifungal drugs. The factors causing dermatomycosis are classified in three distorted genera, Epidermophyton, Microsporum, and Trichophyton.
Dermatophytosis is an infection of the skin, hair, and nails as a result of colonization of the Keratin layers in the body. 2020 14(2):2545-2.ĭermatophytes infections, especially those affecting the keratinized tissues, are a major concern worldwide and are increasing on a global scale.
The distribution of lethal Holstein haplotypes affecting female fertility among the Russian Black-and-White cattle. Keywords: cattle, fertility, genetic defects, Holstein haplotypesĬitation: Khatib A, Mazur AM, Prokhortchouk E. Such management leads to avoid the economic losses and to decrease the frequency of the mutant alleles in the cattle population. It helps breeders to make an appropriate mating decision by mating only carriers to non-carriers. This has a significant importance in breeding programs. No carriers were detected for DUMPS.Ĭonclusions: This work represented an important attempt for extensively screening the occurrence of various genetic defects among the Russian dairy cattle. The occurrence was relatively high for some defects such as BY, HCD, HH1 and HH3 with a carrier frequency of 4.11, 5.66, 2.96 and 2.88%, respectively. Results: The results clearly showed the presence of these defects among the Russian Black-and-White animals. The first one is genotyping the animals using the bovine DNA chips that contain the mutations and the second one is the polymerase Chain Reaction (PCR). Two methods were used for identification of carriers of mutations.
Materials and Methods: 1991 animals (1500 bulls and 491 cows) of the Russian Black-and-White cattle were included in the study. In this study, we will investigate the occurrence of 10 lethal recessive Holstein haplotypes HH0 (BY), HH1, HH2, HH3, HH4, HH5, HCD, HHC (CVM), HHB (BLAD) and HHD (DUMPS) among the Russian Black-White cattle, and we will determine the carrier frequency and the frequency of the mutant alleles for these haplotypes. The occurrence of these defects among the Russian dairy cattle has never been extensively screened before. These defects are now selected against in many countries. Background: Many genetic defects have been discovered and proved to be associated with the decrease of female fertility of dairy cattle.
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